Your Impact

The next-generation gene therapy products Poseida is making are complex, and our gene therapy research and development department combines scientists with a wide range of technical backgrounds. You'll work alongside organic chemists synthesizing novel nanomaterials, formulation scientists devising non-viral delivery platforms, molecular biologists inventing genome engineering tools, and pharmacologists discovering how to deploy Poseida's innovative gene therapy modalities. Your assays will be used to identify promising new nano formulations and treatment strategies, as well as characterize the performance of gene therapy candidates. Our objective is to make gene therapies able to cure severe disease at all stages of life: this is a daunting challenge, and we need your ingenuity to meet it.

Position Summary

Poseida Therapeutics, Inc. is searching for an outstanding Sr. Research Associate to join our highly collaborative Genetic Medicines team. This position offers an excellent opportunity to support preclinical program development as well as develop delivery tools for gene therapy applications in an exciting and dynamic environment focused on cutting-edge gene editing technology. This person will be engaged in in vivo activities directed toward the discovery and characterization of novel nanoparticles and delivery strategies as well as other proprietary systems for delivering nucleic acids and proteins for in vivo genetic medicines.

Responsibilities

These may include but are not limited to:

• Execute studies in mice and rats in support of in vivo screening and pharmacology projects.
• Execute daily high-throughput in-vivo LNP formulation screening.
• Assist with the management of day-to-day vivarium operations, including interfacing with vivarium/husbandry staff, colony management, and recordkeeping.
• Act as lead person for all vivarium users, reporting to senior management to provide feedback and make suggestions for improvements in throughput, space planning, animal care, and for in vivo optimization.
• Work cross-functionally with other departments such as formulations and product development teams to execute studies.
• Ability to work on multiple projects at once
• Attention to detail and excellent documentation skills

Requirements, Knowledge, Skills and Abilities

• Bachelor's or master's degree in biology, molecular or cell biology, pharmacology or other relevant scientific discipline with 5 plus years of experience working in a biopharmaceutical drug discovery and development setting with experimental rodent species. High School degree with 10 plus years experience may be considered
• Demonstrated hands-on expertise in routine small animal techniques, particularly tail vein injection, retro-orbital bleeding, submandibular venipuncture, induction/maintenance of anesthesia, whole body perfusion, and necropsy/tissue collection, is necessary
• Prior experience executing routine high-throughput in-vivo formulation screening; preference for experience handling LNPs
• Prior experience executing routine pharmacological endpoint assays, including ELISA, in vivo bioluminescence imaging (BLI), and Western blotting is desired
• Direct experience in rodent models of at least one of the following diseases is preferred: inborn errors of metabolism, hepatofibrotic and other liver disorders, solid or blood cancers, hemoglobin-linked disorders, neuromuscular disease, or cystic fibrosis
• Familiarity with USDA, PHS, and AAALAC guidance on use of animals in research
• Travel between Poseida and vivarium (1.5 miles)

Senior RA In Vivo Gene Therapy $88,000 to $102,750

The final pay offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience with the industry, education, geographic location, etc.

Who We Are and What We Do

Based in San Diego, Poseida Therapeutics is a clinical-stage biopharmaceutical company utilizing our unique and proprietary genetic engineering platform technologies to create next-generation cell and gene therapies with the capacity to cure. We are passionate about making an impact on patients' lives with the development of our CAR-T therapies in various cancers and gene therapies for rare diseases. Our goal is to deliver potential single treatment cures for patients in need. Our portfolio of product candidates is specifically designed to overcome the limitations of current generation cell and gene therapeutics.

At Poseida we put people first. Our team is passionate about improving patients' lives through innovation. See what our team has to say about our culture:

"My favorite part about Poseida is all the people that I get to work with. Everyone is so passionate about what we're doing here and there's so much camaraderie. It feels like one big enthusiastic family."

"My favorite part about working at Poseida is the amazing culture and working environment. Everybody is friendly, professional, collaborative, and has a remarkable can-do and positive attitude."

As we advance our compelling pipeline, there are endless opportunities for impact and growth. We encourage you to apply today!

Recruitment Fraud Alert

Alert: Beware of Employment Scams

Poseida Therapeutics, Inc. has received reports of employment-related scams. These scams have appeared in forms of false job advertisements and/or unsolicited contacts via communication/chat platforms, phone, email or text from individual(s) claiming to be or represent Poseida's Human Resources team. Be advised that Poseida Therapeutics does not extend unsolicited employment offers. Furthermore, Poseida Therapeutics does not request payment information or charge prospective employees any fees during the recruitment process.

If you would like to pursue employment opportunities with Poseida Therapeutics, Inc., please visit our official careers website https://poseida.com/careers-culture/ or official Poseida Therapeutics LinkedIn page. Job postings that do not link directly to our careers website or official Poseida LinkedIn page are not legitimate and might be fraudulent. You may report fraudulent job advertisements or contacts via our Contact Us page at https://poseida.com/contact-us/ and select the subject "Careers." If you have been defrauded or suspect identity theft as a result of an employment scam, please contact your local law enforcement agency for guidance.